A cooling system (20) includes a media exchanger (50), a cooling section (22), and a cooling circuit (120) for circulating a cooling fluid (130) between the media exchanger (50) and the cooling section (22). The media exchanger (50) receives outside air (38) and the cooling section (22) receives return air (32) from and interior space (34). When the cooling fluid (130) circulates into the cooling section (22) via the cooling circuit (120), the temperature of the return air (32) is reduced through indirect heat transfer between the cooling fluid (130) and the return air (32) to produce conditioned air (84). The conditioned air (84) is provided as supply air (46) into the interior space (34). When the cooling fluid circulates into the media exchanger via the cooling circuit, the temperature of the cooling fluid is reduced through direct heat transfer between the cooling fluid and the outside air.