A memory data hole enabled management system includes a host subsystem with memory devices. A remote access controller subsystem identifies memory locations in the memory devices that include data holes, and generates an aggregated multi-device memory location table that associates the memory locations with continuous addresses. The host system then receives first instructions from the remote access controller subsystem to store data across the plurality of memory locations and in response, operates in a block mode to store the data across the memory locations via the aggregated multi-device memory location table. The host subsystem may then receive second instructions from the remote access controller subsystem to access the data across the memory locations and, in response, operate in the block mode to access the data across the memory locations via the aggregated multi-device memory location table.