Systems and methods are disclosed herein to provide improved placement of components in programmable logic devices (PLDs). In one example, a computer-implemented method includes receiving a design identifying operations to be performed by a PLD. The method also includes determining a layout comprising positions of components of the PLD configured to perform the operations. The method also includes performing a timing analysis on the layout. The method also includes selectively adjusting the positions of the components using the timing analysis. Related systems and non-transitory machine-readable mediums are also provided.