Invention Grant
- Patent Title: Enteroinvasive E. coli bacteriophage Esc-COP-4 and use thereof for inhibiting proliferation of enteroinvasive E. coli
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Application No.: US15538588Application Date: 2015-12-28
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Publication No.: US10265356B2Publication Date: 2019-04-23
- Inventor: Seong Jun Yoon , Sang Hyeon Kang , Soo Youn Jun , Hyoun Rok Paik , Jee Soo Son , Byung Kuk Kim , Hee Jeong Shin , Dong Min Kang
- Applicant: Intron Biotechnology, Inc.
- Applicant Address: KR Gyeonggi-Do
- Assignee: INTRON BIOTECHNOLOGY, INC.
- Current Assignee: INTRON BIOTECHNOLOGY, INC.
- Current Assignee Address: KR Gyeonggi-Do
- Agency: Ballard Spahr LLP
- Priority: KR10-2014-0192984 20141230
- International Application: PCT/KR2015/014332 WO 20151228
- International Announcement: WO2016/108542 WO 20160707
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12N7/02 ; A61K35/76 ; A23L2/38 ; A23K20/195 ; A23K10/16 ; A01N63/00 ; C02F3/34 ; A23K10/18 ; A23K50/30 ; A61P31/04 ; C02F103/02

Abstract:
The present invention relates to a Myoviridae bacteriophage Esc-COP-4 that is isolated from the nature and can kill specifically enteroinvasive E. coli strains, which has a genome represented by the nucleotide sequence of SEQ. ID. NO: 1 (Accession NO: KCTC 12663BP), and a method for preventing and treating the infections of enteroinvasive E. coli using the composition comprising said bacteriophage as an active ingredient.
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