Invention Grant
- Patent Title: Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
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Application No.: US15402795Application Date: 2017-01-10
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Publication No.: US10265371B2Publication Date: 2019-04-23
- Inventor: Antonio Pedro Villaverde Corrales , Esther Vazquez Gomez , Maria Virtudes Cespedes Navarro , Isolda Casanova Rigat , Neus Ferrer Miralles , Ramon Mangues Bafalluy , Ugutz Unzueta Elorza
- Applicant: UNIVERSITAT AUTONOMA DE BARCELONA , INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU , CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA, BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Applicant Address: ES Barcelona ES Barcelona ES Zaragoza
- Assignee: UNIVERSITAT AUTONOMA DE BARCELONA,INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU,CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Current Assignee: UNIVERSITAT AUTONOMA DE BARCELONA,INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU,CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Current Assignee Address: ES Barcelona ES Barcelona ES Zaragoza
- Agency: Greer, Burns & Crain, Ltd.
- Priority: EP11382005 20110113
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K47/00 ; C07K7/08 ; C07K14/00 ; C12N15/62 ; C12N15/86 ; C07K14/435 ; A61K47/62 ; A61K47/66
Abstract:
Conjugates comprising a targeting moiety specific for the CXCR4 and based on the polyphemusin-derived peptide and a therapeutic or imaging agent are provided. Therapeutic and diagnostic methods with the conjugates which require specific targeting to CXCR4+ cells are provided as well.
Public/Granted literature
- US20170209590A1 METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS Public/Granted day:2017-07-27
Information query
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