The subject matter of the present invention relates generally to a vehicle that has axles with tires mounted thereon with at least one axle that is a lift axle, and more specifically, to a method that optimizes the effective tire rolling resistance by adjusting the load on the tires, resulting in an improvement in the fuel economy of the vehicle. According to one embodiment, the method takes into consideration the rolling resistance characteristics of the tires placed onto the axles of the vehicle and provides an algorithm for optimizing their rolling resistance by raising or lowering the lift axle.