Invention Grant
- Patent Title: Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof
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Application No.: US15750205Application Date: 2016-08-31
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Publication No.: US10266496B2Publication Date: 2019-04-23
- Inventor: Xinye Yang , Changwei Huang , Facheng Ma , Ji Zhang , Xiaojun Wang , Yingjun Zhang
- Applicant: SUNSHINE LAKE PHARMA CO., LTD.
- Applicant Address: CN Dongguan, Guangdong
- Assignee: SUNSHINE LAKE PHARMA CO., LTD.
- Current Assignee: SUNSHINE LAKE PHARMA CO., LTD.
- Current Assignee Address: CN Dongguan, Guangdong
- Agency: Kam Wah Law
- Priority: CN201510560190 20150902
- International Application: PCT/CN2016/097660 WO 20160831
- International Announcement: WO2017/036404 WO 20170309
- Main IPC: C07D215/48
- IPC: C07D215/48 ; C07D215/02 ; C07D235/08 ; C07D237/28 ; C07D249/18 ; C07D261/20 ; C07D263/54 ; C07D209/04 ; C07D291/08 ; C07D263/56 ; C07D317/64 ; C07D231/56 ; C07D333/54 ; C07D333/62 ; C07D235/06 ; C07D471/04 ; C07D487/04 ; C07D209/08 ; C07D209/10 ; C07D277/64 ; C07D209/30 ; C07D307/79 ; C07D307/82 ; C07D209/42 ; C07D213/79 ; C07D215/06 ; C07D215/16 ; C07D215/18 ; C07D237/30 ; C07D277/56 ; C07D307/83 ; C07D307/84 ; C07D307/85 ; C07D317/68 ; C07D333/70 ; C07D405/04 ; A61K31/33 ; A61K31/404 ; A61K31/343 ; A61K31/36 ; A61K31/381 ; A61K31/4192 ; A61K31/42 ; A61K31/428 ; A61K31/437 ; A61K31/44 ; A61K31/517 ; A61K31/519 ; A61K31/277 ; A61K31/416 ; A61K31/4184 ; A61K31/423 ; A61K31/426 ; A61K31/4418 ; A61K31/443 ; A61K31/502 ; A61K45/06 ; C07C255/57 ; A61K31/47 ; A61P13/02

Abstract:
Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.
Public/Granted literature
- US20180230102A1 CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF Public/Granted day:2018-08-16
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