Invention Grant
- Patent Title: 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-I-yl) ureas as P38 mapkinase inhibitors
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Application No.: US15812425Application Date: 2017-11-14
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Publication No.: US10266519B2Publication Date: 2019-04-23
- Inventor: Kazuhiro Ito , Catherine Elisabeth Charron , John King-Underwood , Stuart Thomas Onions , Alistair Ian Longshaw , Rudy Broeckx , Walter Filliers , Alex Copmans
- Applicant: RESPIVERT LIMITED
- Applicant Address: GB Buckinghamshire
- Assignee: RESPIVERT LIMITED
- Current Assignee: RESPIVERT LIMITED
- Current Assignee Address: GB Buckinghamshire
- Agency: McDermott Will & Emery LLP
- Priority: EP11183682 20111003; EP11183688 20111003; EP12168395 20120516; EP12168396 20120516
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/12 ; A61K31/4155 ; C07D491/10 ; A61K31/215 ; A61K31/351 ; A61K31/513 ; A61K31/506
Abstract:
There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.
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