- Patent Title: Use of metalloproteinase inhibitors against bacterial infections
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Application No.: US15322838Application Date: 2015-07-03
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Publication No.: US10279017B2Publication Date: 2019-05-07
- Inventor: Mark Salzig , Andreas Vilcinskas , Rainer Fischer
- Applicant: Fraunhofer-Gesellschaft zur Foederung der angewand Forschung e.V.
- Applicant Address: DE Munich
- Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
- Current Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
- Current Assignee Address: DE Munich
- Agency: Wagenknecht IP Law Group PC
- Priority: EP14175566 20140703
- International Application: PCT/EP2015/065210 WO 20150703
- International Announcement: WO2016/001410 WO 20160107
- Main IPC: A61L2/16
- IPC: A61L2/16 ; A01N43/16 ; A01N63/02 ; A61K38/57 ; A61K45/06 ; A61K48/00 ; C07K14/81 ; A61K31/7036
Abstract:
A composition comprising as components a polypeptide IMPIα (including wild type) and/or a polypeptide IMPIα-fusion and at least one antibiotic compound, in particular an aminoglycoside antibiotic, and/or at least one bactericidal compound, wherein the polypeptides, the at least one antibiotic and the at least one bactericidal compound is present in the composition in concentrations which exhibit in combination a synergistic effect against resistant bacteria.
Public/Granted literature
- US20170136107A1 USE OF METALLOPROTEINASE INHIBITORS AGAINST BACTERIAL INFECTIONS Public/Granted day:2017-05-18
Information query
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