Invention Grant
- Patent Title: Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder
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Application No.: US15429585Application Date: 2017-02-10
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Publication No.: US10279051B2Publication Date: 2019-05-07
- Inventor: Steven A. Goldman
- Applicant: University of Rochester
- Applicant Address: US NY Rochester
- Assignee: University of Rochester
- Current Assignee: University of Rochester
- Current Assignee Address: US NY Rochester
- Agency: Pepper Hamilton LLP
- Main IPC: C12N5/07
- IPC: C12N5/07 ; A61K35/30 ; A61K45/06 ; A61K49/00 ; C12N5/079 ; G01N33/50 ; A01K67/027 ; A61K35/545
Abstract:
The present application relates to a non-human mammal model of a human neurodegenerative disorder, methods of producing the non-human mammal model, and methods of using the non-human mammal model to identify agents suitable for treating a neurodegenerative disorder. The present application also relates to methods of treating neurodegenerative disorders and restoring normal brain interstitial potassium levels.
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