Invention Grant
- Patent Title: Compositions and related methods for modulating alkaloid production by controlling PMT promoter activation mediated by transcriptional factors ERF and MYC
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Application No.: US15644199Application Date: 2017-07-07
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Publication No.: US10280203B2Publication Date: 2019-05-07
- Inventor: Michael Paul Timko , Paul J Rushton , Sheng-Cheng Han , Hongbo Zhang , Marta Tatiana Bokowiec
- Applicant: University of Virginia Patent Foundation
- Applicant Address: US VA Charlottesville
- Assignee: University of Virginia Patent Foundation
- Current Assignee: University of Virginia Patent Foundation
- Current Assignee Address: US VA Charlottesville
- Agency: Buchanan Ingersoll & Rooney LLP
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07K14/415
Abstract:
Compositions and methods for modifying the production levels of alkaloids in plants are provided. Alkaloid production can be genetically controlled by modulating the transcriptional activation of PMT genes mediated by members of the ERF family and/or Myc family of transcription factors. Novel nucleotide sequences encoding the Myc family of transciption factors are also provided.
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