Invention Grant
- Patent Title: Class of stable heptamethine cyanine fluorophores and biomedical applications thereof
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Application No.: US15524567Application Date: 2014-11-05
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Publication No.: US10280307B2Publication Date: 2019-05-07
- Inventor: Martin John Schnermann , Roger Rauhauser Nani , James Blaine Shaum
- Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Applicant Address: US DC Washington
- Assignee: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2014/064136 WO 20141105
- International Announcement: WO2016/072984 WO 20160512
- Main IPC: A61K49/00
- IPC: A61K49/00 ; C09B23/08 ; C07D209/10 ; C07D209/12 ; C07D209/14 ; C09K11/06 ; G01N33/58

Abstract:
Embodiments of C4′-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4′-alkyl-ether heptamethine cyanine fluorophores also are disclosed.
Public/Granted literature
- US20180273758A1 NEW CLASS OF STABLE HEPTAMETHINE CYANINE FLUOROPHORES AND BIOMEDICAL APPLICATIONS THEREOF Public/Granted day:2018-09-27
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