Invention Grant
- Patent Title: Method for using heat-resistant mismatch endonuclease
-
Application No.: US16217581Application Date: 2018-12-12
-
Publication No.: US10280412B2Publication Date: 2019-05-07
- Inventor: Kiyoyuki Matsumura , Nariaki Takatsu , Takashi Uemori , Hiroyuki Mukai
- Applicant: TAKARA BIO INC.
- Applicant Address: JP Shiga
- Assignee: TAKARA BIO INC.
- Current Assignee: TAKARA BIO INC.
- Current Assignee Address: JP Shiga
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2013-052265 20130314
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12Q1/683 ; C12P19/34
Abstract:
Provided are a mismatch-specific cleavage reaction using a novel heat-resistant mismatch nuclease, a method for removing errors in a nucleic acid amplification reaction using the mismatch nuclease, a method for inhibiting the amplification of a nucleic acid having a specific base sequence during a nucleic acid amplification reaction, and a method for detecting a nucleic acid having a single-base polymorphic mutation using this inhibition method.
Public/Granted literature
- US20190100736A1 METHOD FOR USING HEAT-RESISTANT MISMATCH ENDONUCLEASE Public/Granted day:2019-04-04
Information query
