- Patent Title: Minicircle DNA recombinant parental plasmid having genetically engineered antibody gene expression cassette, a minicircle DNA having the expression cassette, and applications
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Application No.: US14909060Application Date: 2014-08-05
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Publication No.: US10280425B2Publication Date: 2019-05-07
- Inventor: Zhiying Chen , Fei Ma , Chengyi He
- Applicant: Shenzhen Institutes of Advanced Technology , Shenzhen Hornetcorn Biotechnology Company, Ltd.
- Applicant Address: CN Nanshan Shenzhen, Guangdong CN Futian Shenzhen, Guangdong
- Assignee: Shenzhen Institutes of Advanced Technology,Shenzhen Hornetcorn Biotechnology Company, Ltd.
- Current Assignee: Shenzhen Institutes of Advanced Technology,Shenzhen Hornetcorn Biotechnology Company, Ltd.
- Current Assignee Address: CN Nanshan Shenzhen, Guangdong CN Futian Shenzhen, Guangdong
- Agency: Bozicevic, Field & Francis LLP
- Agent Bret E. Field
- Priority: CN201310339305 20130806
- International Application: PCT/CN2014/083741 WO 20140805
- International Announcement: WO2015/018331 WO 20150212
- Main IPC: C12N15/10
- IPC: C12N15/10 ; C12N15/64 ; C12N15/70 ; C12N15/85

Abstract:
Provided are a minicircle DNA recombinant parental plasmid having a genetically engineered antibody gene expression cassette and a preparation method for the plasmid, a minicircle DNA having the genetically engineered antibody gene expression cassette, a preparation method for the DNA, and applications thereof, and, a host cell having the minicircle DNA, a preparation method for the cell, and applications thereof. Also provided are a genetically engineered antibody, a preparation method for same, and applications thereof.
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