Disclosed are various embodiments for determining whether food in a refrigerator has spoiled. An application executing on a computing device receives an image from a refrigerator of a compartment of the refrigerator. The application then analyzes the image to identify a food item in the image. Subsequently, the application analyzes the image to identify a potentially spoiled area of the food item. The application then compares the potentially spoiled area of the food item to a model of a spoiled food item. Afterwards, the application determines that the identified food item has spoiled based at least in part on a comparison of the potentially spoiled area of the identified food item to the model of the spoiled food item.