Invention Grant
- Patent Title: Polyporus squamosus-derived recombinant lectin specific for sialic acid linkage
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Application No.: US15037637Application Date: 2014-11-14
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Publication No.: US10281460B2Publication Date: 2019-05-07
- Inventor: Seonghun Kim
- Applicant: Korea Research Institute of Bioscience and Biotechnology
- Applicant Address: KR Daejeon
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejeon
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: KR10-2013-0140154 20131118
- International Application: PCT/KR2014/010973 WO 20141114
- International Announcement: WO2015/072785 WO 20150521
- Main IPC: C07K14/375
- IPC: C07K14/375 ; G01N33/53 ; G01N33/569
Abstract:
The present invention relates to a method for producing a Polyporus squamosus-derived PSL1b recombinant lectin, which binds specifically to sialic acid containing glycoconjugates, from an Escherichia coli PSL1b strain (deposit number: KCTC12507BP) or a Pichia pastoris PSL1b strain (deposit number: KCTC12500BP) and a lectin produced thereby. The recombinant lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors, or oligosaccharides having sialic acid moieties.
Public/Granted literature
- US20160290997A1 Polyporus Squamosus-Derived Recombinant Lectin Specific for Sialic Acid Linkage Public/Granted day:2016-10-06
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