Selective purging of entries of structures associated with address translation. A request to purge entries of a structure associated with address translation is obtained. Based on obtaining the request, a determination is made as to whether selective purging of the structure associated with address translation is to be performed. Based on determining that selective purging is to be performed, one or more entries of the structure associated with address translation are purged. The selectively purging includes clearing the one or more entries of the structure associated with address translation for a host of the computing environment and leaving one or more entries of one or more guest operating systems in the structure associated with address translation. The one or more guest operating systems are managed by the host.