Invention Grant
- Patent Title: Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
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Application No.: US15092086Application Date: 2016-04-06
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Publication No.: US10292935B2Publication Date: 2019-05-21
- Inventor: Ann Hsu , Liang C. Dong , Amy Ding , Suneel Gupta
- Applicant: Impax Laboratories, Inc.
- Applicant Address: US NJ Bridgewater
- Assignee: Impax Laboratories, Inc.
- Current Assignee: Impax Laboratories, Inc.
- Current Assignee Address: US NJ Bridgewater
- Agency: Florek & Endres PLLC
- Agent Martin Endres
- Main IPC: A61K9/48
- IPC: A61K9/48 ; A61K9/16 ; A61K9/50 ; A61K31/198 ; A61K9/00 ; A61K31/216 ; A61K45/06

Abstract:
The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer and externally coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.
Public/Granted literature
- US20160287523A1 MUCO-ADHESIVE, CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND/OR ESTERS OF LEVODOPA AND USES THEREOF Public/Granted day:2016-10-06
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