A full-servo multi-axis mold clamping device for a die-casting machine, including at least one main body, including a servo motor, actuating arm and mold fixing slide block, one end of the servo motor having a deceleration mechanism coupled eccentrically to the actuating arm, another end of the actuating arm being coupled pivotally to the mold fixing slide block; whereby, the actuating arm is driven to rotate to drive the mold fixing slide block to move to and fro when the servo motor is running.