A C-type CNC machine center generally includes a chassis, a displaceable table, a work table, a working spindle, a coupling seat, and a driver device. The chassis has a working area, a power area, and a displacement channel communicating with the working area and the power area. The displaceable table is slidably mounted to the chassis and located in the working area. The coupling seat is slidably coupled to the base seat in the power area and includes an elongate hollow body and is fixedly mounted, with an end thereof, to the displaceable table. The driver device includes a motor mounted to the base seat in the power area and a ball screw coupled to the motor and the coupling seat to drive the coupling seat and the displaceable table to synchronously conduct reciprocal movement in a given direction. The coupling seat separates the ball screw from the working area.