Methods, apparatus, and articles of manufacture to control and monitor a folding wingtip actuation system are disclosed. An example apparatus includes a collection module to obtain flight stage information of an aircraft. The example apparatus further includes a sequence and control module to calculate a first position of a folding wingtip assembly operatively coupled to a wing of the aircraft, determine actions during a first stage and a second stage to complete in sequence to move the folding wingtip assembly, determine a status of a component of the folding wingtip assembly based on a measurement of a sensor, and control a movement of the folding wingtip assembly in accordance with the actions and based on the status.