Invention Grant
- Patent Title: Substituted boronic acids and boronate esters as immunoproteasome inhibitors
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Application No.: US15516424Application Date: 2015-10-01
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Publication No.: US10294246B2Publication Date: 2019-05-21
- Inventor: Markus Klein , Oliver Schadt , Philipp Haselmayer , Michael Busch
- Applicant: MERCK PATENT GMBH
- Applicant Address: DE Darmstadt
- Assignee: MERCK PATENT GMBH
- Current Assignee: MERCK PATENT GMBH
- Current Assignee Address: DE Darmstadt
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP14003392 20141001
- International Application: PCT/EP2015/002008 WO 20151001
- International Announcement: WO2016/050359 WO 20160407
- Main IPC: A61K31/69
- IPC: A61K31/69 ; C07F5/02 ; A61P17/06 ; A61P11/06 ; A61P37/06 ; A61P19/02 ; A61P35/02 ; A61P11/00 ; A61P29/00 ; A61P35/00
Abstract:
Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.
Public/Granted literature
- US20180105539A1 BORONIC ACID DERIVATIVES Public/Granted day:2018-04-19
Information query
