Invention Grant
- Patent Title: Compound, composition, and method for detecting caspase activity and/or apoptosis
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Application No.: US14183480Application Date: 2014-02-18
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Publication No.: US10294271B1Publication Date: 2019-05-21
- Inventor: H. Charles Manning , Matthew R. Hight
- Applicant: Vanderbilt University
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Stites & Harbison PLLC
- Agent Richard S. Myers, Jr.
- Main IPC: A61K38/06
- IPC: A61K38/06 ; A61K38/07 ; A61K38/00 ; A61P43/00 ; G01N33/573 ; A61K38/04 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C07K5/10 ; C07K5/08
Abstract:
Molecular probe suitable for quantification of caspase activity in vivo using positron emission tomography (PET). Embodiments of the present invention can detect apoptosis in tumors and as a novel, potentially translatable biomarker for predicting response to personalized medicine.
Information query
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