Invention Grant
- Patent Title: Foreign DNA surveillance protein
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Application No.: US14888853Application Date: 2014-05-05
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Publication No.: US10294480B2Publication Date: 2019-05-21
- Inventor: David M. Knipe , Megan Horn Orzalli
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US MA Cambridge
- Agency: Nixon Peabody LLP
- Agent David S. Resnick
- International Application: PCT/US2014/036835 WO 20140505
- International Announcement: WO2014/179807 WO 20141106
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/63 ; C12N15/11 ; C12N15/113 ; G01N33/50
Abstract:
A method for augmenting expression of a heterologous nucleic acid in a eukaryotic cell or increasing the efficiency of gene expression using any gene expression system is carried out by decreasing expression or activity of an endogenous Interferon-induced protein-16 (IFI16).
Public/Granted literature
- US20160076041A1 Foreign DNA Surveillance Protein Public/Granted day:2016-03-17
Information query
