Invention Grant
- Patent Title: Identification of nucleic acid template-linked barcodes comprising nucleic acid modifications
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Application No.: US14863133Application Date: 2015-09-23
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Publication No.: US10294523B2Publication Date: 2019-05-21
- Inventor: Benjamin Flusberg , Jonas Korlach , Jeffrey Wegener , Tyson A. Clark , Igor Drasko Vilfan , Andrey Kislyuk , Stephen Turner , Jon Sorenson , Kevin Travers , Cheryl Heiner , Austin B. Tomaney , Patrick Marks , Jessica Lee , Lei Jia , Dale Webster , John Lyle , Jeremiah Hanes
- Applicant: Pacific Biosciences of California, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Pacific Biosciences of California, Inc.
- Current Assignee: Pacific Biosciences of California, Inc.
- Current Assignee Address: US CA Menlo Park
- Agent David C. Scherer
- Main IPC: C12Q1/689
- IPC: C12Q1/689 ; C12Q1/6837 ; C12Q1/6858 ; C12Q1/6869 ; C12Q1/6874
Abstract:
Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Public/Granted literature
- US20160153038A1 CLASSIFICATION OF NUCLEIC ACID TEMPLATES Public/Granted day:2016-06-02
Information query
IPC分类:
