Methods, systems, and computer program products for detecting hand-eye coordination in real time by combining camera eye tracking and wearable sensing are provided herein. A computer-implemented method includes determining an eye gaze path of an individual during a given period of time by measuring (i) any eye movements made by the individual during the given period of time and (ii) any head movements made by the individual during the given period of time; measuring any hand movements made by the individual during the given period of time; performing a spatio-temporal analysis of the determined eye gaze path and the measured hand movements to compute a hand-eye coordination value attributable to the individual; and outputting the computed hand-eye coordination value to at least one user.