Disclosed are an AMOLED pixel driving circuit and a pixel driving method. The AMOLED pixel driving circuit utilizes the 4T2C structure, and comprises: a first thin film transistor (T1), a second thin film transistor (T2), a third thin film transistor (T3), a fourth thin film transistor (T4), a first capacitor (C1), a second capacitor (C2) and an organic light emitting diode (D1); the nth scan signal (SCAN(n)) and the n+1th scan signal (SCAN(n+1)) are combined with each other, and correspond to a threshold voltage sensing stage, a holding stage, a programming stage and a drive stage one after another. In comparison with the pixel driving circuit of the 5T2C structure, the corresponding thin film transistor is controlled merely with arranging the scan signal. There will be the compensation function, and the amount of the control signals can be decreased, and the circuit structure is simplified and the cost is decreased.