A method and/or electrochemical cell for utilizing one or more gas diffusion 5 electrodes (GDEs) in an electrochemical cell, the one or more gas diffusion electrodes have a wetting pressure and/or a bubble point exceeding 0.2 bar. The one or more gas diffusion electrodes can be subjected to a pressure differential between a liquid side and a gas side. A pressure on the liquid side of the GDE over the gas side does not exceed the wetting pressure of the GDE during 10 operation (in cases where a liquid electrolyte side has higher pressure), and/or a pressure on the gas side of the GDE over the liquid side, does not exceeds the bubble point of the GDE (in cases where the gas side has the higher pressure).