The technology described herein enhances the operation of a wireless Radio Frequency (RF) system to dynamically modify Automatic Gain Control (AGC) based on RF characteristics of a received data signal. In one implementation, a method of operating a wireless RF system includes receiving a data signal and applying AGC based on AGC thresholds. The method further includes determining an RF characteristic of the data signal, determining signal inflections and signal magnitudes of the RF characteristic during a time window, and comparing the signal inflections and signal magnitudes to an AGC signal inflection threshold and AGC signal magnitude threshold, respectively. The method further provides widening the AGC thresholds if the signal inflections and signal magnitudes exceed the AGC inflection and magnitude thresholds, respectively.