Invention Grant
- Patent Title: Tablet comprising 7-[4-(4-benzo[b]thiopen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof
-
Application No.: US15713427Application Date: 2017-09-22
-
Publication No.: US10307419B2Publication Date: 2019-06-04
- Inventor: Yoshiharu Inoue
- Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
- Current Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: JP2011-227057 20111014
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K9/20 ; A61K9/28 ; A61K9/00
![Tablet comprising 7-[4-(4-benzo[b]thiopen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof](/abs-image/US/2019/06/04/US10307419B2/abs.jpg.150x150.jpg)
Abstract:
This invention relates to a tablet containing, as an active ingredient, 7-[4-(4-benzo[b]thiophen-4-yl -piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof, that has excellent disintegration ability, storage stability and photostability.The tablet of the present invention comprising an uncoated tablet containing 7-[4-(4-benzo[b]thiophen-4 -yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof as an active ingredient, excipients such as lactose, corn starch, and microcrystalline cellulose; disintegrants such as low-substituted hydroxypropylcellulose, croscarmellose sodium, and sodium carboxymethyl starch; binders such as hydroxypropylcellulose; lubricants such as stearate; and further comprising a coating layer, containing hypromellose; talc; titanium oxide; colorant; and the like, the coating layer being applied to the surface of the uncoated tablet.
Public/Granted literature
Information query
IPC分类: