Invention Grant
- Patent Title: Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
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Application No.: US15924831Application Date: 2018-03-19
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Publication No.: US10307422B2Publication Date: 2019-06-04
- Inventor: Roland Werner Bürli , William Rameshchandra Krishna Esmieu , Christopher James Lock , Karine Fabienne Malagu , Andrew Pate Owens , William E. Harte
- Applicant: USHER III INITIATIVE, INC.
- Applicant Address: US IL Chicago
- Assignee: USHER III INITIATIVE, INC.
- Current Assignee: USHER III INITIATIVE, INC.
- Current Assignee Address: US IL Chicago
- Agency: Cooley LLP
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/5025 ; A61K31/40 ; C07C251/86 ; C07D519/00 ; G01N33/50 ; G01N33/68 ; A61K31/165 ; A61K31/167

Abstract:
Compounds, compositions and methods for the treatment of retinal degenerative diseases, such as retinitis pigmentosa, Leber's congenital Amaurosis, Syndromic retinal degenerations, age-related macular degeneration and Usher Syndrome, and hearing loss associated with Usher Syndrome are described herein.
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