Invention Grant
- Patent Title: Methods for treatment of vascular endothelial dysfunction using nicotinamide mononucleotide
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Application No.: US15126548Application Date: 2015-03-24
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Publication No.: US10307437B2Publication Date: 2019-06-04
- Inventor: Douglas R. Seals , Lindsey Gano , Natalie Poliektor
- Applicant: The Regents of the University of Colorado, a Body Corporate
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a Body Corporate
- Current Assignee: The Regents of the University of Colorado, a Body Corporate
- Current Assignee Address: US CO Denver
- Agency: Foley Hoag LLP
- Agent David P. Halstead
- International Application: PCT/US2015/022267 WO 20150324
- International Announcement: WO2015/148522 WO 20151001
- Main IPC: A61K31/706
- IPC: A61K31/706

Abstract:
This invention is about the compositions and methods for assessing and treating vascular endothelial dysfunction. Various aspects provide a method for treatment of vascular endothelial dysfunction, comprising administering a composition comprising nicotinamide mononucleotide and a pharmaceutical excipient to a subject. In one embodiment the dose is administered to subjects in response to the indicator. In another embodiment the dose is administered chronically to subjects.
Public/Granted literature
- US20170087171A1 METHODS FOR TREATMENT OF VASCULAR ENDOTHELIAL DYSFUNCTION USING NICOTINAMIDE MONONUCLEOTIDE Public/Granted day:2017-03-30
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