Invention Grant
- Patent Title: Modified MGLUR6 promoter and methods of use
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Application No.: US15125066Application Date: 2015-03-11
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Publication No.: US10307492B2Publication Date: 2019-06-04
- Inventor: Zhuo-Hua Pan , Qi Lu , Tushar H. Ganjawala , JrGang Cheng
- Applicant: Wayne State University
- Applicant Address: US MI Detrot
- Assignee: Wayne State University
- Current Assignee: Wayne State University
- Current Assignee Address: US MI Detrot
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/US2015/019985 WO 20150311
- International Announcement: WO2015/138616 WO 20150917
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K38/17 ; A61K9/00 ; C07K14/705 ; C12N15/86 ; C12N15/67 ; C12N15/85
Abstract:
The invention provides nucleic acids and nucleic acid expression vectors containing optimized mGluR6 promoters for expression of transgenes in the retina. The compositions and methods of the invention are useful for expression of gene products to preserve, improve, or restore phototransduction or vision.
Public/Granted literature
- US20170021038A1 A MODIFIED MGLUR6 PROMOTER AND METHODS OF USE Public/Granted day:2017-01-26
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