- Patent Title: Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs
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Application No.: US15529996Application Date: 2015-11-25
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Publication No.: US10308634B2Publication Date: 2019-06-04
- Inventor: Ulrich Bothe , Holger Siebeneicher , Nicole Schmidt , Reinhard Nubbemeyer , Ulf Bömer , Judith Günther , Holger Steuber , Martin Lange , Christian Stegmann , Andreas Sutter , Alexandra Rausch , Christian Friedrich , Peter Hauff
- Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
- Applicant Address: DE Berlin
- Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee Address: DE Berlin
- Agency: Morrison & Foerster LLP
- Priority: EP14195032 20141126
- International Application: PCT/EP2015/077596 WO 20151125
- International Announcement: WO2016/083433 WO 20160602
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4439 ; A61P19/02 ; C07F7/18 ; C07D405/14

Abstract:
The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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