Invention Grant
- Patent Title: Inhibitors of PTP4A3 for the treatment of cancer
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Application No.: US15737062Application Date: 2016-06-16
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Publication No.: US10308663B2Publication Date: 2019-06-04
- Inventor: John S. Lazo , Elizabeth R. Sharlow , Kelley E. McQueeney , Peter Wipf , Joseph M. Salamoun
- Applicant: John S. Lazo , Elizabeth R. Sharlow , Kelley E. McQueeney , Peter Wipf , Joseph M. Salamoun
- Applicant Address: US VA Charlottesville US PA Pittsburgh
- Assignee: University of Virginia Patent Foundation,University of Pittsburgh —Of the Commonwealth System of Higher Education
- Current Assignee: University of Virginia Patent Foundation,University of Pittsburgh —Of the Commonwealth System of Higher Education
- Current Assignee Address: US VA Charlottesville US PA Pittsburgh
- Agency: Schwegman Lundberg & Woessner, P.A.
- International Application: PCT/US2016/037895 WO 20160616
- International Announcement: WO2016/205534 WO 20161222
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/4365 ; A61P35/00

Abstract:
The invention provides protein tyrosine phosphatase inhibitor compounds, Their pharmaceutical compositions, uses, and methods of use, such as in the treatment of various cancers, and process for making the compounds. Also disclosed is an improved synthesis of protein tyrosine phosphatase inhibitor and precursor compound thienopyridone (5).
Public/Granted literature
- US20180170946A1 INHIBITORS OF PTP4A3 FOR THE TREATMENT OF CANCER Public/Granted day:2018-06-21
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