Invention Grant
- Patent Title: Cell-penetrating compstatin analogs and uses thereof
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Application No.: US14775663Application Date: 2014-03-14
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Publication No.: US10308687B2Publication Date: 2019-06-04
- Inventor: Cedric Francois , Pascal Deschatelets , Monica Gerber
- Applicant: Apellis Pharmaceuticals, Inc.
- Applicant Address: US KY Crestwood
- Assignee: Apellis Pharmaceuticals, Inc.
- Current Assignee: Apellis Pharmaceuticals, Inc.
- Current Assignee Address: US KY Crestwood
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; Rolando Medina
- International Application: PCT/US2014/027289 WO 20140314
- International Announcement: WO2014/152391 WO 20140925
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/12 ; C07K7/64 ; C07K7/08 ; C07K14/47 ; C07K14/005 ; C07K14/475 ; C12N7/00 ; G01N33/564 ; A61K47/64
Abstract:
In some aspects, the present invention cell-penetrating compstatin analog and compositions comprising cell-penetrating compstatin analog. In some aspects, the invention further provides methods of using cell-penetrating compstatin analogs treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ, to inhibit production or release of biologically active C3 cleavage products.
Public/Granted literature
- US20160215022A1 CELL-PENETRATING COMPSTATIN ANALOGS AND USES THEREOF Public/Granted day:2016-07-28
Information query
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