Invention Grant
- Patent Title: Variants of DR3 and use thereof
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Application No.: US15306822Application Date: 2015-04-27
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Publication No.: US10308703B2Publication Date: 2019-06-04
- Inventor: Amir Aharoni , Itay Levin
- Applicant: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
- Applicant Address: IL Beer-Sheva
- Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY I
- Current Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY I
- Current Assignee Address: IL Beer-Sheva
- Agency: The Roy Gross Law Firm, LLC
- Agent Roy Gross
- International Application: PCT/IL2015/050435 WO 20150427
- International Announcement: WO2015/166486 WO 20151105
- Main IPC: C07K14/715
- IPC: C07K14/715 ; C12N5/10 ; C12N15/11 ; C07K14/705 ; A61K38/00
Abstract:
Death-domain receptor 3 (DR3) variants having increased binding affinity to TL1A, and composition comprising same, are provided. Further, methods of use of said peptides or composition, including, but not limited to treatment of autoimmune and/or inflammatory disease are provided.
Public/Granted literature
- US20170114118A1 VARIANTS OF DR3 AND USE THEREOF Public/Granted day:2017-04-27
Information query
