Invention Grant
- Patent Title: Chelate compounds and their synthetic methods
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Application No.: US15324904Application Date: 2015-09-29
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Publication No.: US10308725B2Publication Date: 2019-06-04
- Inventor: Yuzo Nishida
- Applicant: DISEASE ADSORPTION SYSTEM TECHNOLOGIES CO., LTD.
- Applicant Address: JP Kanazawa-shi, Ishikawa
- Assignee: DISEASE ADSORPTION SYSTEM TECHNOLOGIES CO., LTD.
- Current Assignee: DISEASE ADSORPTION SYSTEM TECHNOLOGIES CO., LTD.
- Current Assignee Address: JP Kanazawa-shi, Ishikawa
- Agency: Yokoi & Co., U.S.A.
- Agent Toshiyuki Yokoi
- Priority: JP2014-198609 20140929
- International Application: PCT/JP2015/077468 WO 20150929
- International Announcement: WO2016/052488 WO 20160407
- Main IPC: C08B37/08
- IPC: C08B37/08 ; C07H15/18 ; A61K31/722 ; G01N33/20 ; B01D21/01 ; A61K9/00 ; A61K9/06

Abstract:
A chelate compound wherein a chelate-forming moiety is attached to a base compound having an amino group and at least a part of the amino group is in the form of a halide salt. A specific example of the halide salt is hydrochloride. As the base compound, a chitosan having a glucosamine skeleton is preferred. Also, chitosan beads are usable. The chelate compound is produced by reacting the base compound having an amino group with an aldehyde group of an aromatic cyclic compound, aromatic cyclic compound having at least a functional group capable of forming a chelate and the aldehyde group, to form a Schiff base, reducing the Schiff base with a reducing agent and then treating with a hydrohalogenic acid (hydrochloric acid).
Public/Granted literature
- US20170210828A1 CHELATE COMPOUNDS AND THEIR SYNTHETIC METHODS Public/Granted day:2017-07-27
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