Invention Grant
- Patent Title: Stablized EZH2 peptides
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Application No.: US14772143Application Date: 2014-03-13
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Publication No.: US10308926B2Publication Date: 2019-06-04
- Inventor: Loren D. Walensky , Gregory H. Bird , Woojin Kim , Stuart Orkin
- Applicant: DANA-FARBER CANCER INSTITUTE, INC.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2014/025587 WO 20140313
- International Announcement: WO2014/151369 WO 20140925
- Main IPC: C12N9/96
- IPC: C12N9/96 ; A61K38/00 ; A61K35/00 ; A61K38/12 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C07K14/47 ; C12N9/10
Abstract:
Provided herein are polypeptides containing stabilized therapeutic peptides related to enhancer of zeste homolog 2 (EZH2), histone lysine N-methyltransferase. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
Public/Granted literature
- US20160068834A1 STABLIZED EZH2 PEPTIDES Public/Granted day:2016-03-10
Information query
