- Patent Title: Compositions with improved intravitreal half-life and uses thereof
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Application No.: US15990542Application Date: 2018-05-25
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Publication No.: US10308943B2Publication Date: 2019-06-04
- Inventor: Carl Erickson , Christopher P. Rusconi , Kevin G. McLure , Renta Hutabarat
- Applicant: Vitrisa Therapeutics, Inc.
- Applicant Address: US CA Larkspur
- Assignee: Vitrisa Therapeutics, Inc.
- Current Assignee: Vitrisa Therapeutics, Inc.
- Current Assignee Address: US CA Larkspur
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C12N15/113 ; C12N15/115 ; A61K9/00 ; A61K31/7088 ; A61K31/7105 ; A61K31/711 ; A61K47/54 ; A61P27/02
Abstract:
Provided herein are compositions and methods for the treatment of retinal diseases. The compositions and methods include a therapeutic agent conjugated to a vitreous component binding moiety. The vitreous component binding moiety may be an aptamer or a small molecule that binds to a structural component of the vitreous humor (e.g., hyaluronic acid, collagen or vitronectin).
Public/Granted literature
- US20180340179A1 COMPOSITIONS WITH IMPROVED INTRAVITREAL HALF-LIFE AND USES THEREOF Public/Granted day:2018-11-29
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