- Patent Title: Whole-cell system for cytochrome P450 monooxygenases biocatalysis
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Application No.: US14898655Application Date: 2014-06-17
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Publication No.: US10308972B2Publication Date: 2019-06-04
- Inventor: Adrian Gerber , Frank Hannemann , Sabrina Bleif , Michael Kleser , Rita Bernhardt
- Applicant: Sanofi
- Applicant Address: FR Gentilly
- Assignee: SANOFI CHIMIE
- Current Assignee: SANOFI CHIMIE
- Current Assignee Address: FR Gentilly
- Agency: McDonell Boehnen Hulbert & Berghoff LLP
- Priority: EP13305814 20130617
- International Application: PCT/EP2014/062749 WO 20140617
- International Announcement: WO2014/202627 WO 20141224
- Main IPC: C12P33/16
- IPC: C12P33/16 ; C12P33/00 ; C12N1/21 ; C12N9/02 ; C12P7/62 ; C12N9/10
Abstract:
The subject of the present invention is a whole-cell catalysis process for converting substrates of cytochrome P450 monooxygenases of eukaryotic origin into valuable biotechnological products. The subject of the present invention is also microorganisms genetically engineered to achieve those biotransformations with high rates and processes to prepare these microorganism strains.
Public/Granted literature
- US20160376625A1 Whole-Cell System For Cytochrome P450 Monooxygenases Biocatalysis Public/Granted day:2016-12-29
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