A system and method adjust instruction dispatch in a multi-pipeline processor core having a plurality of execution units for improved performance of out-of-order execution of instructions. A dispatch adjust circuit receives a queue full signal from one or more of the execution queues that indicates the corresponding execution queue is full. In response to the queue full signal, the instruction dispatch circuit sends a stop signal to the instruction issuer to stop issuing additional instructions to the queues until one or more of the queues are empty. The dispatch adjust circuit may also receive a queue empty signal from the queues to detect when they are empty to send a start signal to the issuer.