A low PAPR sequence design method for a wireless communication system includes the following steps: setting relevant parameters of a designed sequence at first, then carrying out multiple iterations, generating multiple length-designated sequences having elements 0 and 1 and obeying the Bernoulli distribution of designated probability density parameters according to the parameters during primary iteration, screening the generated sequences according to the PAPRs of the sequences, updating the parameters of the next iteration based on the screened sequences, and finally mapping the sequence having the minimum PAPR to obtain a sequence with a low PAPR with elements of −1 and 1 after terminating the iterations. Compared with the prior art, the present invention allows the design of a sequence with a low PAPR with an arbitrary length, and the sequence only contains +1 and −1 as elements and has good autocorrelation performance.