A camera for a vision system of a vehicle includes a housing, an imager and a lens assembly. The imager is disposed in the housing and includes a pixelated imaging array having a plurality of photosensing elements. The imager captures image data. The lens assembly is disposed at the housing. The imager is disposed at an adjustment device in the housing. The adjustment device is operable, responsive to a control signal, to adjust a position of the imager relative to the housing and the lens assembly.