An image sensor includes a first pixel and a second pixel. The first pixel receives a first signal sensed by a first photodiode. The second pixel receives a second signal sensed by a second photodiode. A pixel binning device includes a first transistor, a second transistor and a binning circuit, wherein the first transistor switchably couples to the first pixel to transfer the first signal, the second transistor switchably couples to the second pixel to transfer the second signal, and the binning circuit couples to the first transistor and the second transistor to bin the first signal and the second signal.