Systems and methods to support intra-application flow prioritization are disclosed herein. User equipment (UE) may be configured to communicatively couple to an Evolved Universal Terrestrial Radio Access Network (E-UTRAN) Node B (eNB). The eNB may transmit packets from the UE to an evolved packet core (EPC), which may transmit schedule packets to an application function (AF) via a network. The AF may provide classification information and prioritization information for a plurality of intra-application flows transmitted between the AF and the UE. The EPC may classify uplink and/or downlink traffic into the intra-application flows and mark and/or schedule the traffic based on the prioritization information. Absolute and/or modular length, payload values, and/or packet type may be used to classify the traffic into the intra-application flows.