Invention Grant
- Patent Title: IMiD screening methods IMiD-sensitive cells with mutant CRBN
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Application No.: US15955073Application Date: 2018-04-17
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Publication No.: US10334829B2Publication Date: 2019-07-02
- Inventor: Benjamin Levine Ebert , Jan Krönke , Steven A. Carr , Namrata D. Udeshi , Emma Fink
- Applicant: THE BROAD INSTITUTE, INC. , THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: The Broad Institute, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee: The Broad Institute, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Greenberg Traurig, LLP
- Agent Melissa Hunter-Ensor; Leslie Serunian
- Main IPC: G01N33/00
- IPC: G01N33/00 ; A01K67/027 ; C12Q1/6886 ; G01N33/50 ; G01N33/574 ; G01N33/94 ; C12Q1/6876
Abstract:
The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof.
Public/Granted literature
- US20180343839A1 KNOCK-IN RODENT COMPRISING A MUTATION IN AN ENDOGENOUS CRBN LOCUS AND METHODS OF USE THEREOF Public/Granted day:2018-12-06
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