- Patent Title: Treatment of neurodegenerative diseases through inhibition of HSP90
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Application No.: US12307063Application Date: 2007-07-02
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Publication No.: US10336757B2Publication Date: 2019-07-02
- Inventor: Gabriela Chiosis , Paul Greengard , Fei Dou , Wenjie Luo , Huazhong He , Danuta Zatorska
- Applicant: Gabriela Chiosis , Paul Greengard , Fei Dou , Wenjie Luo , Huazhong He , Danuta Zatorska
- Applicant Address: US NY New York US NY New York
- Assignee: Sloan-Kettering Institute for Cancer Research,The Rockefeller University
- Current Assignee: Sloan-Kettering Institute for Cancer Research,The Rockefeller University
- Current Assignee Address: US NY New York US NY New York
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; John P. Rearick
- International Application: PCT/US2007/072671 WO 20070702
- International Announcement: WO2008/005937 WO 20080110
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/52 ; A01N43/54 ; C07D239/42 ; C07D401/04 ; A01N43/50 ; A61K31/415 ; A01N43/30 ; A61K31/36 ; C07D473/40
Abstract:
Treatment of neurodegenerative diseases is achieved using small molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-brain barrier or are other wise delivered to the brain.
Public/Granted literature
- US20090298857A1 Treatment of Neurodegenerative Diseases Through Inhibition of HSP90 Public/Granted day:2009-12-03
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