Invention Grant
- Patent Title: Pyrimidine compounds and methods using the same
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Application No.: US15317999Application Date: 2015-06-15
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Publication No.: US10336768B2Publication Date: 2019-07-02
- Inventor: Gregory D. Cuny , Marcie A. Glicksman , Kevin J. Hodgetts , Steven L. Mathieu , Yukari Y. Perrella , Vincent Darmency , Hrvoje Lusic
- Applicant: Yuma Therapeutics, Inc. , The Brigham and Women's Hospital, Inc.
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: Yuma Therapeutics, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee: Yuma Therapeutics, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Clark & Elbing LLP
- International Application: PCT/US2015/035735 WO 20150615
- International Announcement: WO2015/192119 WO 20151217
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D487/04 ; C07D405/04 ; C07D239/42 ; C07D239/70 ; C07D471/04 ; C07D239/84 ; C07D251/16 ; C07D251/22 ; C07D405/10
Abstract:
The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.
Public/Granted literature
- US20170107228A1 PYRIMIDINE COMPOUNDS AND METHODS USING THE SAME Public/Granted day:2017-04-20
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