A system and method for cylinder deactivation in a multi-cylinder diesel engine comprises pumping air in to an intake manifold of the diesel engine using a turbocharger. Air is pumped in to the intake manifold using an intake air assisting device. And, fuel injection is selectively deactivated to at least one of the cylinders in the diesel engine. An intake valve and an exhaust valve is selectively deactivated for the at least one of the cylinders of the diesel engine.